Artificial sweeteners and many more health issues plus diabetes


. The inconsistency in the treatment of veterans of colour with type 2 diabetes compared to white veterans, according to a review of VHA data.


. The risk of hyperactivity


. Children of obese moms were more likely to have attention deficit hyperactivity disorder (11.4 vs 16.4 per cent) than those of normal-weight mothers.


. According to the new studies


. A survey conducted on artificial sweeteners


. Conclusion





Disparities in Diabetes Medication, Pregnancy Weight and Attention Deficit Hyperactivity Disorder, and the Use of Artificial Sweeteners

A new review of Veterans Health Administration data reveals that many veterans, particularly those of colour, lack access to the most modern and effective medications for treating type 2 diabetes. Children of overweight or diabetic moms may have twice the risk of developing ADHD, according to recent studies (ADHD). Furthermore, a large-scale French investigation suggests that the consumption of artificial sweeteners may be associated with an elevated threat of cardiovascular disease and stroke.

Newer diabetic drugs are less likely to be prescribed to black veterans.





The inconsistency in the treatment of veterans of colour with type 2 diabetes compared to white veterans, according to a review of VHA data.


Two newer and very effective types of medicine, sodium-glucose cotransporter-2 inhibitors (SGLT2 inhibitors) and glucagon-like peptide-1 receptor agonists, were less likely to be provided to Black and Hispanic/Latino veterans than they were to white veterans, the study revealed (GLP-1 receptor agonists). Recent studies have shown that newer medications for type 2 diabetes help stabilise blood glucose levels and can decrease the risk of cardiovascular disease and the advancement of chronic renal disease.





data of patients using a new medicine

Nearly 12 million persons (96% male) with type 2 diabetes who made at least two visits to a VHA primary care clinic between January 1, 2019, and December 31, 2020, were included in the observational research. The median age of the sample was 68.


Very few patients have been prescribed the most recent medications; only 10.7% of patients were given an SGLT2 inhibitor, and 7.7% were given a GLP-1 receptor agonist. Race and ethnicity made a big difference, though.


Prescription rates for SGLT2 inhibitors and GLP-1 receptor agonists were 11.3% and 8.2%, respectively, among white veterans, and 8.8% and 6.1%, respectively, among Black veterans. The percentage of veterans who were given a GLP-1 receptor agonist was also lower among Hispanic/Latino veterans (7.1% vs 7.8%).


Previous studies have shown racial and ethnic differences in the usage of specific diabetes drugs.
the expert's opinion


The authors concluded that more study was required to determine whether or not there was a correlation between prescription rates and clinical outcomes.


Pregnant women who are overweight and acquire diabetes are twice as likely to have a kid with attention deficit hyperactivity disorder.


The risk of hyperactivity


The researches show that those women who are over weighted their children have more risk of hyperactivity.


A significant risk factor for ADHD in children is maternal obesity. Increased risk of attention deficit hyperactivity disorder in offspring has also been associated with gestational diabetes. About 30% of women are obese at their first prenatal checkup, which rises to 47% among those who develop gestational diabetes. The current research confirms that maternal obesity is a significant risk factor for having a kid with attention deficit hyperactivity disorder in this cohort.


Mother obesity and infants health issues


According to a study by researchers at the Hospital Universitari Mutua Terrassa in Barcelona, Spain, children of those mothers who were overweight or obese during pregnancy were more likely to develop behavioural and emotional problems later in life. With a healthy pregnancy weight increase, "we could not discover this relationship."





Between 1991 and 2009, researchers analysed data on 1,036 infants who were delivered to mothers who had been diagnosed with gestational diabetes. A median of 17.7 years was spent keeping tabs on the kids. ADHD was diagnosed in 13% (135) of the population.


Using the conventional body mass index (BMI) scale,


 each woman was placed into one of four categories based on her initial weight (before pregnancy weight gain): underweight (BMI 18.5), average weight (18.5 - 24.9), overweight (25 - 29.9), or obese ( 30.0). (BMI 30 or higher). As the National Academy of Medicine suggested, gaining more than the maximum allowed during pregnancy is excessive.


Children of obese moms were more likely to have attention deficit hyperactivity disorder (11.4 vs 16.4 per cent) than those of normal-weight mothers.


 Women who developed extra weight during pregnancy were the only ones who showed a correlation between gestational diabetes and obesity, and attention deficit hyperactivity disorder. Children of mothers with average weight gain during pregnancy while having gestational diabetes or obesity were not shown to be at increased risk for attention deficit hyperactivity disorder.


Dr Perera view


Dr Perea said in the announcement, "Clinicians should educate their patients on the necessity of appropriate weight increase during pregnancy."


Risk factors for cardiovascular disease and stroke may include artificial sweeteners.


According to the new studies


A new study published in BMJ advises that you give those artificial sweeteners some severe thought. Many individuals ingest these chemicals daily since they are included in a wide variety of foods and drinks, such as diet soda, yoghurt, cereal, candy, and ketchup.


The current study suggests a connection between artificial sweeteners and an increased risk of cardiovascular illness, including heart attack and stroke, in contrast to prior studies that have connected their usage to obesity, high blood pressure, cholesterol and many more health issues.





A survey conducted on artificial sweeteners


More than one hundred thousand participants (mean age 42) from France participated in the online NutriNet-Santé research. Nearly all of them were women. At baseline and every six months after that, participants completed 24-hour dietary questionnaires to evaluate their food consumption and artificial sweetener use. Additional information, such as lifestyle, exercise routine, general health, and more, was gathered at the start of the trial and six-month intervals over the next nine years.


Only a third of the people surveyed claimed to regularly use artificial sweeteners, and those who did consume an average of 42 milligrams (mg) per day. That's roughly the same as 3.4 ounces of diet drink or one packet of sugar substitute (a typical can is 12 oz.). At least 77 milligrams per day was considered high usage of artificial sweeteners, whereas 7 milligrams or less was considered modest consumption.





The conclusion of the survey


After nine years of observation, researchers discovered that daily consumption of artificial sweeteners was connected with an elevated risk of cardiovascular disease and cerebrovascular disease, which includes stroke. People who ingested the most aspartame (Equal, NutraSweet) were shown to have a greater stroke risk than those who consumed the least of these sweeteners. Sucralose (Splenda) and acesulfame potassium (found in many sugar-free drinks) consumers who used significant quantities of these sweeteners were shown to have a greater risk of coronary heart disease than those who consumed little to no sucralose.


Overall, the study did not find any protective effect of using artificial sweeteners instead of added sugars against cardiovascular disease.





Conclusion


In keeping with the current view of various health organisations, the authors concluded that "the data show that these food additives, ingested daily by millions of people and present in many juices and processed food, should not be regarded as a healthy and safe substitute to sugar."


Since this was observational research, the authors concede that they cannot prove a cause-and-effect relationship between artificial sweeteners and cardiovascular disease.


Some data suggest that maternal consumption of artificial sweeteners may increase their child's chance of becoming overweight or obese. While the American Heart Association and the American Diabetes Association both say that artificial sweeteners may be part of a balanced diet, consumers must remember that "sugar-free" doesn't automatically imply "good."